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The case for regulating indispensable amino acid metabolism: the branched-chain α-keto acid dehydrogenase kinase-knockout mouse.

The case for regulating indispensable amino acid metabolism: the branched-chain α-keto acid dehydrogenase kinase-knockout mouse

BCAAs (branched-chain amino acids) are indispensable (essential) amino acids that are required for body protein synthesis. Indispensable
amino acids cannot be synthesized by the body and must be acquired from the diet…Twenty amino acids are required for protein synthesis.
In man and mammals, nine amino acids cannot be synthesized endogenously and/or in sufficient amounts. These amino acids, including the BCAAs
(branched-chain amino acids) leucine, isoleucine and valine, must be acquired in the diet and are classified as nutritionally indispensable
(essential) amino acids. If a single indispensable amino acid is limiting, protein synthesis is inhibited. The need of the organism for each
indispensable amino acid for protein synthesis and for non-protein functions defines the individual daily indispensable amino acid requirement…

Link to Source:

The Biochemical Society, London


The case for regulating indispensable amino acid metabolism: the branched-chain α-keto acid dehydrogenase kinase-knockout mouse

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Research: